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In vivo evidence of interaction between interferon-stimulated gene factors and the interferon-stimulated response
1Laboratory of Molecular Cell Biology, Rockefeller University, New York, New York 10021.
Molecular and Cellular Biology
|August 1, 1989
Abstract:
Constitutive and interferon-inducible DNase hypersensitive sites in vivo are located in interferon-stimulated gene promoters near sequences that specifically bind constitutive or interferon-inducible proteins in vitro. Induced sites and proteins are transient or maintained, depending on cell type. Interferon-stimulated gene transcription is transient or maintained in parallel.