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Palatal Swelling: A Diagnostic Enigma.

Ramalingam Suganya1, Narasimhan Malathi1, Harikrishnan Thamizhchelvan1

  • 1Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, Sri Ramachandra University, Tamil Nadu, India.

Case Reports in Dentistry
|December 16, 2016
PubMed
Summary

Giant cell tumors (GCT) are rare bone neoplasms. This study details a unique case of GCT occurring in the palate, a highly unusual location for this bone lesion.

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Area of Science:

  • Oncology
  • Pathology
  • Oral Medicine

Background:

  • Giant cell tumor (GCT) of bone is a distinct bony lesion characterized by numerous osteoclast-type giant cells.
  • GCT typically presents as an expansive, lytic bone lesion without periosteal reaction or significant peripheral sclerosis.
  • While common in long bones and the sacrum, GCT in the palate is exceptionally rare, distinguishing it from other giant cell lesions like those found in the jaws.

Purpose of the Study:

  • To report a unique case of giant cell tumor (GCT) of the palate.
  • To highlight the clinical, radiological, and pathological characteristics of this rare presentation.
  • To differentiate this GCT from other giant cell-containing lesions of the jaw and bone.

Main Methods:

  • Case presentation of a 30-year-old female with GCT of the palate.
  • Review of clinical presentation, imaging findings (radiological features), and histopathological examination.
  • Differential diagnosis considered against other giant cell lesions.

Main Results:

  • A 30-year-old female presented with a GCT of the palate.
  • The lesion exhibited typical GCT characteristics: expansive, lytic, and rich in multinucleated giant cells.
  • This case underscores the palate as an unusual but possible site for GCT.

Conclusions:

  • Giant cell tumor (GCT) of the palate is an exceedingly rare entity.
  • Accurate diagnosis requires careful evaluation of clinical, radiological, and pathological features to distinguish it from other giant cell lesions.
  • This case expands the known anatomical distribution of GCT.