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Timing temporal transitions during brain development.

Anthony M Rossi¹, Vilaiwan M Fernandes¹, Claude Desplan²

¹Department of Biology, New York University, New York, NY 10003, USA.

Current Opinion in Neurobiology

|December 17, 2016

Summary

This summary is machine-generated.

Neural stem cells generate diverse neurons through temporal patterning, an evolutionarily conserved process. Understanding this mechanism aids in directing neural progenitors for brain repair.

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Infant Auditory Processing and Event-related Brain Oscillations

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

Area of Science:

Neuroscience
Developmental Biology
Cell Biology

Background:

Neuronal diversity is crucial for brain function.
Neural stem cells generate diverse neuronal cell types.
Temporal patterning, the sequential production of distinct neuronal fates, is a key mechanism.

Purpose of the Study:

To review recent advances in temporal patterning during neuronal specification.
To focus on conserved players and mechanisms in invertebrate and vertebrate models.
To highlight the evolutionary conservation of temporal patterning.

Main Methods:

Review of recent scientific literature.
Focus on conserved molecular players and mechanisms.
Comparative analysis across invertebrate and vertebrate models.

Main Results:

Temporal patterning is an evolutionarily conserved strategy for generating neuronal diversity.
Identified conserved players and mechanisms governing temporal patterning.
Demonstrated the importance of temporal patterning in neuronal specification.

Conclusions:

Temporal patterning is a fundamental strategy for neuronal diversity across species.
Understanding temporal patterning principles is vital for brain repair applications.
Further research into molecular players can guide directed neural progenitor differentiation.