Related Experiment Video
Updated: Mar 10, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Sutureless Aortic Valve Replacement: An Easy and Safe Approach for Patients with Anomalous Left Circumflex Coronary
Alfredo Giuseppe Cerillo1, Dorela Haxhiademi2, Sergio Berti3
1Operative Unit of Cardiac Surgery, G. Pasquinucci Heart Hospital, Fondazione Toscana G. Monasterio, Massa, Italy.
Insights
An anomalous origin of the left circumflex coronary artery (LCx) from the right sinus of Valsalva poses surgical risks. Sutureless aortic valve replacement using the Perceval S prosthesis may offer advantages in these complex cases.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Devices
Background:
- Anomalous origin of the left circumflex coronary artery (LCx) from the right sinus of Valsalva is a recognized coronary anomaly.
- This condition can lead to significant complications during aortic valve replacement (AVR) procedures, including surgical AVR and transcatheter aortic valve implantation.
- Patients with this anomaly may face increased risks due to the proximity of the LCx ostium to the aortic annulus.
Purpose of the Study:
- To describe the outcomes of patients with anomalous LCx origin undergoing sutureless AVR.
- To evaluate the feasibility and potential benefits of using the Sorin Perceval S prosthesis in this specific patient cohort.
- To discuss the advantages of sutureless AVR in managing complex coronary anomalies during valve replacement.
Main Methods:
- Case series describing four patients with anomalous LCx origin from the right sinus of Valsalva.
- All patients underwent sutureless aortic valve replacement using the Sorin Perceval S prosthesis.
- Perioperative outcomes and potential procedural advantages were assessed.
Main Results:
- Successful sutureless AVR was achieved in all four patients with anomalous LCx origin.
- The Perceval S prosthesis facilitated the procedure, potentially mitigating risks associated with the anomalous coronary artery.
- No major complications directly related to the anomalous coronary artery were reported during the procedures.
Conclusions:
- Sutureless AVR with the Sorin Perceval S prosthesis appears to be a viable and potentially advantageous option for patients with anomalous LCx origin.
- This approach may simplify the surgical procedure and reduce the risk of complications in patients with this coronary anomaly.
- Further studies are warranted to confirm the long-term benefits and safety of this technique in a larger population.
Abstract:
An anomalous origin of the left circumflex coronary artery (LCx) from the right sinus of Valsalva is a frequent coronary problem. This particular condition, though usually silent, is associated with an increased incidence of serious complications during surgical aortic valve replacement (AVR) and transcatheter aortic valve implantation. Here, the cases are described of four patients with an anomalous origin of the LCx from the right sinus of Valsalva who underwent sutureless AVR with the Sorin Perceval S prosthesis. The possible advantages of this approach are also discussed.

