Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lysosomal Hydrolases01:22

Lysosomal Hydrolases

4.7K
Lysosomes are the site for the degradation of macromolecules and biological polymers released during membrane trafficking events such as secretory, endocytic, autophagic, and phagocytic pathways. The membrane-enclosed area of the lysosome, called the lumen, contains hydrolytic enzymes active in an acidic environment. These acid hydrolases are functional at a pH between 4.5 and 5 and are involved in cellular processes such as cell signaling, energy metabolism, restoration of the plasma membrane,...
4.7K
Smooth Endoplasmic Reticulum01:21

Smooth Endoplasmic Reticulum

8.6K
Smooth endoplasmic reticulum or smooth ER is a sub-organelle with specialized functions in animal cells and plant cells. It is often associated with the tubule morphology of the endoplasmic reticulum.
The ER provides optimal conditions for synthesizing steroid hormones and lipids, such as phospholipids and triglycerides. Traditionally, lipid metabolism was considered to be a smooth ER function. However, there is no direct evidence to prove that rough ER is completely excluded from lipid...
8.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Angiolymphoid Hyperplasia with Oeosinophilia Showing Promising Result with Intralesional Radio-frequency Ablation Therapy: A New Cost-effective and Hassle-free Modality of Treatment.

Journal of cutaneous and aesthetic surgery·2017
Same author

Evaluation of Clinical Significance of Dermoscopy in Alopecia Areata.

Indian journal of dermatology·2016
Same author

Basosquamous Carcinoma Masquerading as Angiolymphoid Hyperplasia.

Indian journal of dermatology·2016
Same author

Painful wart in the ear?

Indian dermatology online journal·2016
Same author

Congenital candidiasis.

Indian dermatology online journal·2014
Same author

Initial default among diagnosed sputum smear-positive pulmonary tuberculosis patients in Andhra Pradesh, India.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2008

Related Experiment Video

Updated: Mar 9, 2026

Assay to Measure Nucleocytoplasmic Transport in Real Time within Motor Neuron-like NSC-34 Cells
08:53

Assay to Measure Nucleocytoplasmic Transport in Real Time within Motor Neuron-like NSC-34 Cells

Published on: May 16, 2017

9.2K

Nekam's disease.

Chintaginjala Aruna1, D V S B Ramamurthy1, T Neelima2

  • 1Department of DVL, Katuri Medical College, Guntur, Andhra Pradesh, India.

Indian Dermatology Online Journal
|December 20, 2016
PubMed
Summary
This summary is machine-generated.

Keratosis lichenoides chronica, a rare mucocutaneous disorder, presents as asymptomatic papules. This case report details a 40-year-old male diagnosed with Nekam's disease, highlighting its rarity and varied clinical presentation.

Keywords:
Interface dermatitisKeratosis lichenoids chronicaNekam's disease

More Related Videos

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons
07:43

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons

Published on: January 7, 2019

7.4K
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.7K

Related Experiment Videos

Last Updated: Mar 9, 2026

Assay to Measure Nucleocytoplasmic Transport in Real Time within Motor Neuron-like NSC-34 Cells
08:53

Assay to Measure Nucleocytoplasmic Transport in Real Time within Motor Neuron-like NSC-34 Cells

Published on: May 16, 2017

9.2K
Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons
07:43

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons

Published on: January 7, 2019

7.4K
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.7K

Area of Science:

  • Dermatology
  • Rare Diseases
  • Mucocutaneous Disorders

Background:

  • Keratosis lichenoides chronica (KLC), or Nekam's disease, is an exceptionally rare mucocutaneous disorder.
  • Characterized by asymptomatic violaceous keratotic papules in linear or reticular patterns on the trunk and extremities.
  • Histological findings include interface dermatitis, distinguishing it from other conditions.

Observation:

  • A 40-year-old male patient presented with a complex set of symptoms.
  • The patient exhibited features overlapping with lichen planus, seborrheic dermatitis, and aphthous ulcers.
  • These diverse clinical manifestations prompted a thorough diagnostic workup.

Findings:

  • The diagnostic workup confirmed the patient's condition as Nekam's disease.
  • This case contributes to the limited global literature on KLC, particularly from India.
  • The patient's presentation underscores the varied clinical spectrum of this rare disorder.

Implications:

  • This case highlights the diagnostic challenges posed by rare diseases like KLC.
  • Increased awareness of KLC's varied presentations is crucial for timely diagnosis.
  • Further case reports are needed to better understand the epidemiology and clinical course of Nekam's disease.