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Updated: Mar 9, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
Published on: January 16, 2016
Effects of Co-solvents on Reactions Run under Micellar Catalysis Conditions
Christopher M Gabriel1, Nicholas R Lee1, Florence Bigorne2
1Department of Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Abstract:
The impact of varying percentages of an organic solvent added to reactions run in aqueous nanomicelles as the reaction medium has been investigated. Issues such as rates of reaction, percent conversion, and yield, as well as various practical aspects (e.g., effect on stirring, etc.), are discussed, leading to an operationally simple method for the general improvement of potentially problematic systems across a broad range of reaction types, in particular for reactions run at scale.
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