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Updated: Mar 9, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
A Left-to-Right Shunt After Transfemoral TAVR Using Edwards SAPIEN 3
Julius Steffen1, Anton Köhler2, Florian Schwarz3
1Department of Cardiology, Ludwig Maximilians University (LMU), Munich, Germany. Electrronic correspondence: julius.steffen@med.uni-muenchen.de.
Insights
Transcatheter aortic valve replacement (TAVR) can cause rare cardiac complications. This report details a left-to-right shunt, a potential complication following TAVR for aortic stenosis, managed medically.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Transcatheter aortic valve replacement (TAVR) is a primary treatment for severe aortic stenosis (AS).
- While generally safe, TAVR carries risks including cardiac perforation and shunt formation.
- Left-to-right shunts are a rare but significant complication post-TAVR.
Observation:
- An 87-year-old male patient underwent TAVR for AS using an Edwards SAPIEN S3 prosthesis.
- Echocardiography revealed a small channel, indicative of a left-to-right shunt, originating from the right coronary cusp shortly after the procedure.
- This represents the sixth reported case of such a complication.
Findings:
- The identified complication was a left-to-right shunt post-TAVR.
- The shunt was detected via echocardiography originating from the right coronary cusp.
- The patient's condition was successfully managed through medical intervention.
Implications:
- This case highlights the importance of vigilant echocardiographic monitoring after TAVR to detect rare complications like shunts.
- Medical management can be a viable option for specific cases of post-TAVR left-to-right shunts.
- Understanding and reporting these rare complications aids in refining TAVR procedural safety and patient care strategies.
Abstract:
Transcatheter aortic valve replacement (TAVR) is used for the treatment of aortic stenosis (AS). Besides major bleeding, conduction blocks, stroke or atrial fibrillation, complications include cardiac perforation with possible left-to-right-shunts. Herein is reported the sixth case of a left-to-right shunt in an 87-year-old man who underwent TAVR using a 29 mm Edwards SAPIEN S3 prosthesis to treat AS. Soon after the procedure, a small channel evolving from the right coronary cusp could be detected on echocardiography. The patient was managed medically.

