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Proteomic-based biomarker discovery for development of next generation diagnostics

Akbar Khalilpour1,2, Tugba Kilic3,4,5,6, Saba Khalilpour7

  • 1Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 65 Landsdowne Street, Rm. 265, Cambridge, MA, 02139, USA. akhalilpour@bwh.harvard.edu.

Applied Microbiology and Biotechnology
|December 26, 2016
PubMed
Summary

Proteomics enables disease biomarker discovery using advanced mass spectrometry and microarray technologies. This review covers proteomic approaches for early diagnosis and challenges in developing rapid diagnostic tests.

Keywords:
Biomarker discoveryDiagnostic kitsMicrofluidic systemsProteomic

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