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A Matched Case-Control Study of Risk Factors for Breast Cancer Risk in Vietnam
J Nguyen1, Q H Le2, B H Duong2
1Queen's University, Kingston, ON, Canada; Lakeridge Health, Oshawa, ON, Canada.
International Journal of Breast Cancer
|January 11, 2017
Summary
Breast cancer incidence is rising in Vietnam. Factors like higher BMI and older age at first childbirth are linked to increased breast cancer risk in Vietnamese women.
Area of Science:
- Oncology
- Epidemiology
Background:
- Vietnam traditionally has a low incidence of breast cancer.
- However, incidence is rapidly increasing with economic development.
Purpose of the Study:
- To investigate breast cancer risk factors in Vietnam.
- To compare findings with Western and Asian populations.
Main Methods:
- Matched case-control study conducted at the National Cancer Hospital (BVK) in Hanoi.
- Included 492 breast cancer cases and 1306 controls (age 25-75).
- Data collected via structured interviews and central pathology reporting.
Main Results:
- Analysis included 294 matched pairs; mean age at diagnosis was 46.7 years.
- Positive correlations with breast cancer: lower parity, older age at first parity, increased weight and BMI at age 18, and increased BMI at diagnosis.
- No statistically significant differences in age at first menarche or breastfeeding duration.
Conclusions:
- Breast cancer in Vietnam is associated with some, but not all, established Western risk factors.
- Findings align with other studies on breast cancer in Asian populations.
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