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Multilevel Microdissection and Functional-Structural Profiling of Human Renal Arterial Branches
Published on: September 5, 2025
Radiologic Assessment of Native Renal Vasculature: A Multimodality Review.
Sayf Al-Katib1, Monisha Shetty1, Syed Mohammad A Jafri1
1From the Department of Diagnostic Radiology and Molecular Imaging (S.A., M.S., S.Z.H.J.) and Department of Urology (S.M.A.J.), Beaumont Health, Oakland University William Beaumont School of Medicine, Royal Oak, 3601 W 13 Mile Rd, Royal Oak, MI 48073.
Radiologists play a key role in diagnosing renal vascular conditions like stenosis and fibromuscular dysplasia. Understanding renal vascular anatomy and imaging protocols is crucial for identifying these important variants and pathologies.
Area of Science:
- Radiology
- Vascular Imaging
- Renal Pathology
Background:
- Clinically significant renal vascular variants and pathologies require accurate radiologic diagnosis.
- Renal artery and vein assessment is vital across all imaging modalities, as many conditions lack specific clinical suspicion.
- Familiarity with normal renal vascular anatomy and optimized imaging protocols is essential for effective interpretation.
Purpose of the Study:
- To review common and critical renal vascular conditions encountered in radiologic practice.
- To highlight the importance of imaging in diagnosing renal artery stenosis, fibromuscular dysplasia, aneurysms, and arteriovenous abnormalities.
- To emphasize the radiologist's role in identifying both congenital and acquired renal vascular pathologies.
Main Methods:
- Review of key imaging findings for various renal vascular conditions.
- Discussion of diagnostic criteria for renal artery stenosis using ultrasonography (US).
- Description of imaging features differentiating arteriovenous fistulas from arteriovenous malformations and identifying Nutcracker syndrome.
Main Results:
- Renal artery stenosis, often secondary to atherosclerosis or fibromuscular dysplasia, is a primary cause of hypertension.
- Fibromuscular dysplasia is linked to renal artery hypertension, aneurysms, and dissection, particularly in young women.
- Imaging can detect renal artery aneurysms, pseudoaneurysms, arteriovenous fistulas/malformations, and venous thrombi (bland or tumor), as well as leiomyosarcoma.
Conclusions:
- Accurate interpretation of renal vascular imaging is critical for diagnosing diverse pathologies, from stenosis to tumors.
- Knowledge of normal anatomy and imaging techniques aids in recognizing variants and conditions like Nutcracker syndrome.
- Radiologists are indispensable in managing renal vascular diseases, preventing potentially catastrophic outcomes from overlooked conditions.
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