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Are Gut Microbes Responsible for Post-dieting Weight Rebound?
Julien Chilloux1, Marc-Emmanuel Dumas1
1Faculty of Medicine, Department of Surgery and Cancer, Division of Computational and Systems Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK.
Cell Metabolism
|January 12, 2017
Summary
The gut microbiome influences weight regain after dieting, a phenomenon known as the yo-yo effect. Specific dietary supplements can help reset this weight rebound cycle.
Area of Science:
- Microbiology
- Nutrition Science
- Obesity Research
Background:
- The obesity epidemic presents a significant public health challenge.
- The yo-yo effect, characterized by cycles of weight loss and regain, is a common dieting conundrum.
Purpose of the Study:
- To investigate the role of the gut microbiome in the yo-yo effect.
- To explore the potential of dietary interventions to mitigate weight regain.
Main Methods:
- Analysis of the gut microbiome's role in weight cycling.
- Assessment of dietary supplementations for their impact on weight rebound.
Main Results:
- The gut microbiome is demonstrated to play a critical role in the yo-yo effect.
- Simple dietary supplementations were found to effectively reset the weight-rebound clock.
Conclusions:
- Microbiome-targeted interventions offer a novel strategy to combat the yo-yo effect.
- Dietary supplements can be leveraged to manage weight regain and support long-term weight management.
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