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Migration

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Migration is long-range, seasonal movement from one region or habitat to another. This common strategy, carried out by many different organisms around the world, is an adaptive response that typically corresponds to changes in an organism’s environment, like resource availability or climate. Migrations can involve huge groups of thousands of animals as well as single individuals traveling alone and can range from thousands of kilometers to just a few hundred meters.

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Related Experiment Video

Updated: Mar 8, 2026

A CFSE-based Assay to Study the Migration of Murine Skin Dendritic Cells into Draining Lymph Nodes During Infection with Mycobacterium bovis Bacille Calmette-Guérin

A CFSE-based Assay to Study the Migration of Murine Skin Dendritic Cells into Draining Lymph Nodes During Infection with Mycobacterium bovis Bacille Calmette-Guérin

Published on: October 9, 2016

Cutaneous Larva Migrans.

Alexander K C Leung¹, Benjamin Barankin², Kam L E Hon³

¹The University of Calgary, Alberta Children's Hospital, #200, 233 - 16th Avenue NW, Calgary, Alberta. Canada.

Recent Patents on Inflammation & Allergy Drug Discovery

|January 13, 2017

Summary

This summary is machine-generated.

Cutaneous larva migrans, a common travel-associated skin disease, presents as an itchy, migrating track. Oral ivermectin is the preferred treatment for this zoonotic infestation.

Keywords:

Ancylostoma braziliense Ancylostoma caninum cats dogs hookworm pruritus serpiginous track

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Area of Science:

Dermatology
Tropical Medicine
Parasitology

Background:

Cutaneous larva migrans is a frequent skin condition in travelers returning from tropical areas.
Western physicians may lack familiarity with this parasitic infection.

Purpose of the Study:

To comprehensively review the epidemiology, pathophysiology, clinical presentation, complications, and treatment of cutaneous larva migrans.
To update knowledge on this common travel-related dermatosis.

Main Methods:

Conducted a comprehensive literature search using "cutaneous larva migrans" on PubMed.
Included meta-analyses, RCTs, clinical trials, and reviews.
Searched patent databases for management-related innovations.

Main Results:

Cutaneous larva migrans is a zoonotic disease caused by animal hookworm larvae migrating in the epidermis.
Characterized by intensely pruritic, erythematous, serpiginous tracks, endemic in tropical/subtropical regions.
Diagnosis is primarily clinical, supported by travel history and characteristic lesions. Oral ivermectin is the treatment of choice over topical therapies.

Conclusions:

The pathognomonic sign is the pruritic, serpiginous track.
Oral ivermectin is identified as the most effective treatment option.