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Multicenter neonatal databases: Trends in research uses.

Liza M Creel1, Sean Gregory2,3,4, Catherine J McNeal5,6

  • 1Department of Health Management and Systems Science, School of Public Health & Information Sciences, University of Louisville, Louisville, USA.

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|January 15, 2017
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Summary
This summary is machine-generated.

Large multicenter neonatal databases are crucial for studying premature and low birth weight (LBW) infants. Research on these vulnerable populations has expanded significantly, improving neonatology and community pediatric practices.

Keywords:
NICU databasesNICU outcomesPediatrics outcomesPrematurity

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Area of Science:

  • Neonatal research
  • Perinatal health
  • Pediatric outcomes

Background:

  • High rates of preterm birth (12.7%) and low birth weight (LBW, 8.2%) in the US necessitate improved research and clinical practices.
  • Technological advances have reduced mortality but improving overall rates of prematurity and LBW remains a priority.
  • Studying preterm and LBW infants presents challenges, highlighting the need for robust data sources.

Purpose of the Study:

  • To systematically review and describe three major multi-center neonatal databases.
  • To assess the role of these databases in advancing research and quality improvement for preterm and LBW infants.
  • To provide an overview of the landscape of research utilizing these critical resources.

Main Methods:

  • A comprehensive literature search was conducted using PubMed and Google Scholar from 1990 to August 2014.
  • Studies were included if they utilized one of the specified databases for primary data or comparison.
  • Included studies were categorized by publication year, study design, and research focus.

Main Results:

  • A total of 343 studies published between 1991 and 2014 were identified.
  • There has been a notable increase in studies focusing on premature and LBW infants over time.
  • These databases provide essential evidence supporting both neonatology and community-based pediatric practice.

Conclusions:

  • The expansion of research on preterm and LBW infants is significantly supported by the availability of large, multicenter databases.
  • Consistent study of clinical conditions and outcomes since 1990 indicates dedicated research agendas and resources.
  • These databases facilitate long-term, replicable studies, advancing the understanding and care of vulnerable neonatal populations.