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Updated: Mar 8, 2026

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
Published on: February 19, 2016
A highly sensitive SERS-based platform for Zn(ii) detection in cellular media
Hongjun Zhuang1, Zhenzhen Wang1, Xiangchun Zhang1
1CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, P. R. China. limin@ihep.ac.cn yaozy@ihep.ac.cn zhaoyuliang@ihep.ac.cn.
Abstract:
We report a highly sensitive and selective surface-enhanced Raman scattering (SERS)-based detection of aqueous Zn(ii) ions (limit of detection 10-14 M). Spectral changes for a silver nanoparticle-bound Raman reporter upon Zn(ii) chelation constitutes the assay, which is applied to drinking water and to measurements of cellular uptake of Zn(ii).

