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Transient cortical blindness after intradiscal oxygen-ozone therapy
Agostino Salvatore Vaiano1, Cristiana Valente1, Giacomo De Benedetti2
1Struttura Complessa di Oculistica, Azienda Ospedaliera Santa Croce e Carle di Cuneo, Cuneo, Italy.
Indian Journal of Ophthalmology
|January 24, 2017
Summary
A patient experienced sudden blindness and Anton's syndrome after an oxygen-ozone injection for disc herniation. Symptoms resolved completely within two months, with MRI showing posterior cerebral artery ischemia.
Area of Science:
- Neurology
- Ophthalmology
- Interventional Pain Management
Background:
- Oxygen-ozone therapy is an alternative treatment for lumbar disc herniation.
- Potential complications, though rare, require careful consideration.
Observation:
- A 54-year-old male developed bilateral blindness, headache, nausea, and vomiting immediately following an oxygen-ozone injection for disc herniation.
- The patient exhibited Anton's syndrome, denying visual loss despite its presence.
Findings:
- Magnetic resonance imaging revealed recent ischemic lesions in the bilateral posterior cerebral artery territories.
- Complete visual recovery occurred within a 2-month follow-up period.
Implications:
- This case highlights a rare but severe neurological complication associated with oxygen-ozone injections.
- It underscores the importance of recognizing and managing visual disturbances and neurological deficits post-procedure.
- Further research into the mechanisms and prevention of such complications is warranted.

