Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exon Recombination02:32

Exon Recombination

4.2K
The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon...
4.2K
Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

7.1K
Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
7.1K
Gene Conversion02:08

Gene Conversion

10.8K
Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
10.8K
Genetic Drift03:33

Genetic Drift

44.7K
Natural selection—probably the most well-known evolutionary mechanism—increases the prevalence of traits that enhance survival and reproduction. However, evolution does not merely propagate favorable traits, nor does it always benefit populations.
44.7K
Viral Recombination00:57

Viral Recombination

25.5K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
25.5K
Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

77.1K
Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.
77.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Yang et al. Microstructural Characteristics of High-Pressure Die Casting with High Strength-Ductility Synergy Properties: A Review. <i>Materials</i> 2023, <i>16</i>, 1954.

Materials (Basel, Switzerland)·2026
Same author

Enhancing X-ray Image Classification through Heterogeneous Federated Learning with Natural Image-Augmented Models.

IEEE transactions on pattern analysis and machine intelligence·2026
Same author

The <i>GNB3</i> C825T Polymorphism Is Associated With Decreased Risk of Recurrence of Large-Artery Atherosclerotic Acute Ischemic Stroke.

Journal of the American Heart Association·2026
Same author

Developing and Testing a Brief Mindfulness Just-in-Time Adaptive Intervention to Reduce Stress Among Caregivers of People With Dementia: Quasi-Experimental Study.

JMIR aging·2026
Same author

Exercise as a multiscale recalibration of stress-related homeostatic balance.

Frontiers in neuroscience·2026
Same author

TEX29 is a novel acrosome marker dispensable for spermatogenesis and fertilization in mice.

Journal of assisted reproduction and genetics·2026
Same journal

An Evolutionary Algorithm Assisted by an Ensemble of Pareto-Optimal Surrogate Models.

IEEE transactions on cybernetics·2026
Same journal

A Quantum Self-Attention Neural Network Model on Quantum Circuits.

IEEE transactions on cybernetics·2026
Same journal

Semi-Explicit Solution of Some Discrete-Time Higher-Order-Cost Mean-Field-Type Control.

IEEE transactions on cybernetics·2026
Same journal

A Novel One-Step Small Object Detector for Autonomous Aerial Vehicles.

IEEE transactions on cybernetics·2026
Same journal

Online Data-Driven-Based Optimal Output Tracking Control Without Initial Stabilizing Policy.

IEEE transactions on cybernetics·2026
Same journal

Digital Redesign-Based Interval State Estimation for Continuous Systems With Aperiodic Discrete Measurements.

IEEE transactions on cybernetics·2026
See all related articles

Related Experiment Video

Updated: Mar 8, 2026

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

1.4K

Multiple Exponential Recombination for Differential Evolution.

Xin Qiu, Kay Chen Tan, Jian-Xin Xu

    IEEE Transactions on Cybernetics
    |January 24, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Differential evolution (DE) optimization benefits from a novel multiple exponential recombination crossover operator. This new method enhances the handling of dependent variables, improving performance in complex numerical optimization tasks.

    More Related Videos

    In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity
    09:16

    In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity

    Published on: March 25, 2020

    7.8K
    Molecular Evolution of the Tre Recombinase
    12:02

    Molecular Evolution of the Tre Recombinase

    Published on: May 29, 2008

    10.1K

    Related Experiment Videos

    Last Updated: Mar 8, 2026

    Following the Dynamics of Structural Variants in Experimentally Evolved Populations
    04:52

    Following the Dynamics of Structural Variants in Experimentally Evolved Populations

    Published on: February 3, 2023

    1.4K
    In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity
    09:16

    In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity

    Published on: March 25, 2020

    7.8K
    Molecular Evolution of the Tre Recombinase
    12:02

    Molecular Evolution of the Tre Recombinase

    Published on: May 29, 2008

    10.1K

    Area of Science:

    • Computational intelligence
    • Numerical optimization
    • Metaheuristic algorithms

    Background:

    • Differential evolution (DE) is a widely used population-based metaheuristic for numerical optimization.
    • Existing DE variants primarily use binomial recombination, which struggles with dependent variables.
    • Crossover operations in DE have received limited research attention compared to mutation and adaptation.

    Purpose of the Study:

    • To introduce and analyze a novel crossover operator for Differential Evolution.
    • To address the limitations of traditional binomial recombination in handling dependent variables.
    • To enhance the performance of DE algorithms on complex optimization problems.

    Main Methods:

    • Proposed a new 'multiple exponential recombination' crossover operator for DE.
    • The operator facilitates the exchange of multiple segments between solution vectors.
    • Conducted theoretical analysis and empirical evaluations of the proposed operator's properties.

    Main Results:

    • The multiple exponential recombination operator demonstrates superior performance.
    • It effectively handles problems with unknown or complex variable interrelations.
    • Experimental results confirm the robustness and effectiveness of the new crossover scheme.

    Conclusions:

    • The proposed multiple exponential recombination offers a significant advancement in DE crossover strategies.
    • It provides a more capable approach for optimizing problems with interdependent variables.
    • This research opens new avenues for DE algorithm development and application.