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Incidence and interventions for post-thrombotic syndrome
Jeffrey J Farrell1, Christopher Sutter1, Sidhartha Tavri1
1Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, Ohio 44106, USA.
Cardiovascular Diagnosis and Therapy
|January 27, 2017
Summary
Post-thrombotic syndrome (PTS) is a chronic venous disorder following deep venous thrombosis (DVT). This review covers PTS pathophysiology, diagnosis, and management, emphasizing endovascular treatments for improved patient outcomes.
Area of Science:
- Vascular Medicine
- Venous Thromboembolism Research
- Clinical Management
Background:
- Post-thrombotic syndrome (PTS) is a long-term complication of deep venous thrombosis (DVT).
- PTS significantly impacts patient quality of life and imposes a considerable healthcare burden.
- Symptoms include edema, pain, swelling, skin changes, and limb heaviness.
Purpose of the Study:
- To elaborate on the clinical aspects of post-thrombotic syndrome.
- To detail the pathophysiology, diagnostic work-up, and management strategies for PTS.
- To highlight the role and efficacy of endovascular interventions in PTS management.
Main Methods:
- Review of current literature on PTS pathophysiology and clinical presentation.
- Analysis of diagnostic criteria and imaging modalities for PTS.
- Evaluation of established and emerging treatment options, including endovascular procedures.
Main Results:
- PTS pathophysiology involves venous hypertension and valve damage post-DVT.
- Diagnosis relies on clinical assessment and objective testing.
- Management strategies aim to alleviate symptoms and prevent progression.
Conclusions:
- Effective management of PTS is crucial to reduce morbidity and healthcare costs.
- Endovascular therapies offer promising options for selected PTS patients.
- Further research is needed to optimize treatment algorithms for PTS.
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