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Published on: December 15, 2011
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Acrodermatitis Enteropathica Type-II in Libya.
Indian Journal of Dermatology, Venereology and Leprology
|February 2, 2017
Summary
Acrodermatitis enteropathica, a zinc deficiency disorder, presented in infants through skin lesions. Breastfeeding cessation led to symptom improvement, suggesting maternal milk zinc deficiency.
Area of Science:
- Pediatrics
- Dermatology
- Human Nutrition
Background:
- Acrodermatitis enteropathica (AE) is a rare genetic disorder of zinc malabsorption.
- A familial form, Type II AE, is linked to zinc deficiency in breast milk.
- Clinical presentation includes characteristic skin lesions, particularly around body orifices and extremities.
Purpose of the Study:
- To report a case of suspected Type II acrodermatitis enteropathica in a Libyan infant.
- To highlight the association between maternal zinc secretion and infant health.
- To emphasize the importance of considering nutritional deficiencies in pediatric dermatology.
Main Methods:
- Clinical observation of a 6-month-old girl with characteristic skin lesions.
- Review of family history for similar presentations in siblings.
- Assessment of infant feeding history (breastfeeding and weaning).
Main Results:
- The patient presented with erythematous, scaly, exudative, and crusted lesions on the face, neck, back, perineum, thighs, and legs.
- Two siblings experienced similar symptoms at a similar age.
- Symptoms resolved upon weaning, suggesting a link to breast milk composition.
Conclusions:
- The case strongly suggests Type II acrodermatitis enteropathica due to insufficient zinc in maternal breast milk.
- Early recognition and intervention, including dietary adjustments, are crucial for managing AE.
- This case underscores the critical role of maternal nutrition in infant health, particularly concerning essential trace elements like zinc.
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