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Updated: Mar 8, 2026

In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
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Published on: May 4, 2017

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Real-Life Efficacy, Immunogenicity and Safety of Biosimilar Infliximab

Zsuzsanna Vegh1, Zsuzsanna Kurti, Peter L Lakatos

  • 1First Department of Medicine, Semmelweis University, Budapest, Hungary.

Digestive Diseases (Basel, Switzerland)
|February 2, 2017
PubMed

Recently, the use of biosimilar infliximab (IFX) in the treatment of inflammatory bowel diseases has become widespread in some European and non-European countries. Data on the efficacy, safety and immunogenicity from real-life cohorts are accumulating. The first reports showed similar outcomes in the induction and maintenance of remission, mucosal healing, safety and immunogenicity profile to the originator IFX. In the present review, we aimed to summarize the existing knowledge on the efficacy, safety and immunogenicity profile of biosimilar IFX reported from real-life cohorts.

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