Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Obesity01:24

Obesity

1.5K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.5K
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

1.4K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.4K
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

633
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
633
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

4.8K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
4.8K
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

335
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
335
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

320
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
320

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Peak oxygen consumption achieved at the end of cardiac rehabilitation predicts long-term survival in patients with coronary heart disease.

European heart journal. Quality of care & clinical outcomes·2021
Same author

Cardiac rehabilitation fitness changes and subsequent survival.

European heart journal. Quality of care & clinical outcomes·2018
Same author

Cardiovascular Risk in Patients with Prehypertension and the Metabolic Syndrome.

Current hypertension reports·2018
Same author

Impact of cardiac rehabilitation and exercise training programs in coronary heart disease.

Progress in cardiovascular diseases·2017
Same author

Public Park Spaces as a Platform to Promote Healthy Living: Introducing a HealthPark Concept.

Progress in cardiovascular diseases·2017
Same author

Duration of dual antiplatelet therapy following drug-eluting stent implantation: A systemic review and meta-analysis of randomized controlled trials with longer follow up.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2017

Related Experiment Video

Updated: Mar 8, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

1.4K

Obesity and cardiovascular diseases.

Sergey Kachur1, Carl J Lavie2, Alban de Schutter3

  • 1Department of Graduate Medical Education, Ocala Regional Medical Center, Ocala, FL, USA - Sergey.kachur@gmail.com.

Minerva Medica
|February 3, 2017
PubMed
Summary

Obesity impacts cardiovascular health, but metabolic syndrome absence may mitigate risks. For those with existing heart disease, being overweight or class I obese can improve survival, especially with exercise.

More Related Videos

Author Spotlight: Insights into Cardiometabolic Diseases with Subcutaneous Adipose Tissue Microvasculature Studies
06:35

Author Spotlight: Insights into Cardiometabolic Diseases with Subcutaneous Adipose Tissue Microvasculature Studies

Published on: April 5, 2024

1.7K
A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

1.4K

Related Experiment Videos

Last Updated: Mar 8, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

1.4K
Author Spotlight: Insights into Cardiometabolic Diseases with Subcutaneous Adipose Tissue Microvasculature Studies
06:35

Author Spotlight: Insights into Cardiometabolic Diseases with Subcutaneous Adipose Tissue Microvasculature Studies

Published on: April 5, 2024

1.7K
A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

1.4K

Area of Science:

  • Cardiology
  • Public Health
  • Metabolic Disorders

Background:

  • Rising prevalence of obesity, particularly in childhood, poses significant public health challenges.
  • Obesity's cardiovascular (CV) health effects are often linked to metabolic syndrome components like insulin resistance, dyslipidemia, and hypertension.
  • The relationship between obesity and mortality is complex, influenced by metabolic health and fitness levels.

Purpose of the Study:

  • To examine the multifaceted impact of obesity on cardiovascular health.
  • To investigate the association between obesity, metabolic syndrome, and mortality risk.
  • To evaluate the role of cardiorespiratory fitness in modifying obesity's CV effects.

Main Methods:

  • Review of existing literature on obesity and cardiovascular outcomes.
  • Analysis of data linking obesity, metabolic syndrome, and survival rates.
  • Exploration of therapeutic interventions for obesity-related CV risk factors.

Main Results:

  • Obesity's negative CV effects include accelerated atherosclerosis, ventricular remodeling, and increased risk of stroke, myocardial infarction, and heart failure.
  • In obese individuals without metabolic syndrome, mortality risk may not be elevated.
  • Overweight and class I obesity are associated with improved survival in patients with chronic CV disease, though this is attenuated by higher cardiorespiratory fitness.

Conclusions:

  • Dietary changes and exercise, particularly structured programs like cardiac rehabilitation, are effective in reversing obesity-related CV risk factors.
  • Managing metabolic syndrome components is crucial for mitigating obesity's cardiovascular risks.
  • Cardiorespiratory fitness plays a key role in the interplay between obesity and cardiovascular health outcomes.