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Updated: Mar 7, 2026

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Diet and the Microbiome
Nida Murtaza1, Páraic Ó Cuív1, Mark Morrison1
1The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, 37 Kent St, Brisbane, Queensland 4102, Australia.
Abstract:
The gut microbiota provides a range of ecologic, metabolic, and immunomodulatory functions relevant to health and well-being. The gut microbiota not only responds quickly to changes in diet, but this dynamic equilibrium may be managed to prevent and/or treat acute and chronic diseases. This article provides a working definition of the term "microbiome" and uses two examples of dietary interventions for the treatment of large bowel conditions to emphasize the links between diet and microbiome. There remains a need to develop a better functional understanding of the microbiota, if its management for clinical utility is to be fully realized.
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