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Related Concept Videos

Metastasis02:30

Metastasis

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Related Experiment Video

Updated: Mar 7, 2026

Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis
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Cutaneous Metastasis From Carcinoma Parotid.

S Tharakaram, A Tamilarasi

    Indian Journal of Dermatology, Venereology and Leprology
    |February 7, 2017
    PubMed
    Summary

    A parotid gland adenocarcinoma metastasized to the skin, forming multiple nodules in a 35-year-old male. The patient survived for at least two years post-diagnosis.

    Area of Science:

    • Oncology
    • Dermatology
    • Head and Neck Surgery

    Background:

    • Adenocarcinoma of the parotid gland is a malignant tumor originating in the salivary glands.
    • Metastasis of parotid gland cancer to the skin is a rare but significant clinical finding.
    • Skin metastases can indicate advanced disease and affect prognosis.

    Observation:

    • A 35-year-old male presented with multiple, asymptomatic nodules on the skin.
    • These skin nodules were located over the area of a known parotid gland adenocarcinoma.
    • The nodules were characterized as non-tender on physical examination.

    Findings:

    • The observed skin nodules represented metastatic disease from the primary parotid gland adenocarcinoma.
    • This presentation signifies an unusual pattern of cancer spread.

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  • The patient remained clinically stable for at least two years following the diagnosis of metastatic skin nodules.

    • Implications:

    • This case underscores the importance of considering cutaneous metastasis in patients with advanced parotid gland cancer.
    • It highlights the potential for unusual metastatic patterns in adenocarcinoma.
    • Further research may elucidate the specific mechanisms and prognostic implications of parotid cancer skin metastasis.