Cutaneous Metastases in Bronchogenic Carcinoma (five Case Reports)

Area of Science:

• Oncology
• Dermatology
• Pulmonology

Background:

• Cutaneous metastases are secondary malignant growths originating in the skin from a primary cancer elsewhere in the body.
• Bronchogenic carcinoma, or lung cancer, rarely presents with skin involvement, making such cases noteworthy for their rarity and diagnostic challenges.

Purpose of the Study:

• To report five rare cases of cutaneous metastases originating from bronchogenic carcinoma.
• To analyze the histopathological findings of these skin metastases.
• To discuss the clinical interest and implications of lung cancer presenting with skin lesions.

Main Methods:

• Case series reporting.
• Histopathological examination of skin biopsy specimens.
• Review of clinical data for five patients with confirmed bronchogenic carcinoma and cutaneous metastases.

Main Results:

• Five cases of cutaneous metastases from bronchogenic carcinoma were identified.
• Histopathology revealed adenocarcinoma in three cases and squamous cell carcinoma in two cases.
• The majority of affected patients (4 out of 5) were male.

Conclusions:

• Cutaneous metastases from bronchogenic carcinoma, though uncommon, represent a distinct clinical presentation.
• The histopathological diversity (adenocarcinoma vs. squamous cell carcinoma) in skin deposits reflects the primary lung tumor subtypes.
• These cases underscore the importance of considering metastatic disease in the skin, even from primary lung malignancies.