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[Clinical features of stage D prostatic carcinoma]
N Kobayashi1, K Yoshida, H Saitoh
1Department of Urology, Medical Center of Saitama Medical School.
Hinyokika Kiyo. Acta Urologica Japonica
|September 1, 1989
Summary
Stage D prostatic carcinoma primarily presents with urinary symptoms, even with widespread bone metastasis. Younger patients with advanced prostate cancer experience fewer bone metastasis symptoms, with voiding complaints being prominent.
Area of Science:
- Oncology
- Urology
- Pathology
Context:
- Stage D prostatic carcinoma is characterized by distant metastasis.
- Analysis of 67 cases reveals common metastatic sites and presenting symptoms.
Purpose:
- To analyze clinical and histopathological features of stage D prostatic carcinoma.
- To investigate correlations between metastasis, histopathology, age, and symptoms.
Summary:
- Bone metastasis (92.5%) is most common in stage D prostate cancer, yet primary lesion symptoms like dysuria prevail.
- Lymph node metastasis is higher in poorly differentiated types. Younger patients (<65) show no well-differentiated types and fewer bone metastasis symptoms, with voiding issues prominent.
Impact:
- Highlights the discrepancy between metastatic burden and presenting symptoms in advanced prostate cancer.
- Suggests age-related differences in histopathology and symptom presentation for stage D prostate cancer.
- Informs clinical assessment and patient counseling for advanced prostate cancer.