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Updated: Mar 7, 2026

Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
Bariatric Surgery Restores Gut-Brain Signaling to Reduce Fat Intake
Stephanie Caligiuri1, Paul J Kenny1
1Department of Neuroscience, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029-6574, USA.
Abstract:
Hankir and colleagues (2017) show that gastric bypass surgery in rats enhances the sensitivity of cells in the gut to dietary lipids. In turn, these cells signal to stimulate dopamine neurotransmission in the striatum to inhibit fat consumption. The findings have important implications for the development of non-invasive therapeutics for obesity.
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