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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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Acrodermatitis Enteropathica.

R P C Naik, M Meera Baliga

    Indian Journal of Dermatology, Venereology and Leprology
    |February 18, 2017
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    Summary
    This summary is machine-generated.

    A case of acrodermatitis enteropathica (AE) without significant diarrhea showed an excellent response to oral zinc sulfate therapy. This highlights zinc

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    Area of Science:

    • Dermatology
    • Human Genetics
    • Nutritional Science

    Background:

    • Acrodermatitis enteropathica (AE) is a rare genetic disorder of zinc malabsorption.
    • Typically presents with skin lesions, gastrointestinal symptoms (diarrhea), and immune dysfunction.

    Observation:

    • This report details a unique case of AE presenting without significant diarrhea.
    • The patient exhibited classic skin manifestations consistent with AE.

    Findings:

    • Oral zinc sulfate therapy resulted in a rapid and complete resolution of dermatological symptoms.
    • The absence of significant diarrhea in this case is an atypical presentation for AE.

    Implications:

    • Suggests that AE may present with a variable spectrum of symptoms, including without prominent gastrointestinal issues.
    • Emphasizes the critical role of zinc supplementation in managing AE, regardless of accompanying symptoms.
    • Highlights the importance of considering AE in patients with unexplained skin conditions, even in the absence of diarrhea.