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Updated: Mar 7, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Retinal cavernous haemangioma treated by proton beam therapy
Amir Mahdjoubi1, Rémi Dendale2, Livia Lumbroso-Le Rouic3
1Ophtalmology Department, Institut Curie, 26 Rue d'ULM, 75248, Paris, France. amir.mahdjoubi@gmail.com.
Abstract:
As one of intraocular tumours, retinal cavernous haemangioma is a benign vascular lesion that is mostly unilateral. Very few cases about cavernous haemangioma treatment are reported, and there is currently no consensus on the most effective treatment. This clinical case reports on a 40-year-old male, presenting a peripheral retinal cavernous haemangioma, complicated with a repetitive vitreous haemorrhage causing bad vision. Several therapeutic methods were unsuccessfully attempted to stop haemorrhagic recurrences. Thanks to proton beam irradiation, a good collapse of aneurismal dilatations was obtained, with no recurrence of bleeding. This case study confirms that proton beam therapy is a good alternative in treating cavernous haemangiomas, leading to a total tumour regression without complications.
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