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Removable sinus stent for endoscopic sinus surgery: An animal trial
Dan Yaniv1, Lena Shlosberg, Joseph Flomenblit
1Department of Otolaryngology, Head and Neck Surgery, Rabin Medical Center, Petah Tiqva, Israel.
American Journal of Rhinology & Allergy
|February 25, 2017
Summary
A new composite removable stent shows promise for preventing middle concha lateralization during endoscopic sinus surgery. This study in sheep found the stent safe and effective, with no migration or significant adverse effects, supporting further clinical trials.
Area of Science:
- Otolaryngology
- Biomaterials Science
- Surgical Innovation
Background:
- Endoscopic sinus surgery aims to improve paranasal sinus drainage in chronic sinusitis patients.
- Current metal stents for preventing middle concha lateralization have associated adverse effects.
Purpose of the Study:
- To evaluate the feasibility and safety of a novel composite removable stent.
- Assess the stent's performance in preventing middle concha lateralization.
Main Methods:
- A composite removable stent was implanted in the ethmoid cavity of nine sheep following ethmoidectomy.
- Stability, ease of removal, and adverse effects were assessed.
- Histological analysis compared implantation and non-implantation sites.
Main Results:
- No stent migration or displacement occurred.
- No infections or mucosal damage were observed after 4 weeks.
- Histology revealed only mild inflammation, no epithelial damage, and no necrosis.
Conclusions:
- The composite removable stent demonstrated safety and efficacy in a sheep model.
- The promising results warrant further investigation in human patients undergoing endoscopic sinus surgery for chronic sinusitis.
