Related Experiment Video
Updated: Mar 7, 2026

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
Published on: July 11, 2025
The Benefits and Challenges of an Interfaced Electronic Health Record and Laboratory Information System: Effects on
Athena K Petrides, Ida Bixho, Ellen M Goonan
1From the Departments of Pathology (Drs Petrides, Tanasijevic, and Melanson and Mss Bixho and Goonan), Medicine (Ms Bixho, Drs Bates and Lipsitz, and Mr Shaykevich), and Emergency Medicine (Dr Landman), Brigham and Women's Hospital, Boston, Massachusetts; and Harvard Medical School, Boston, Massachusetts (Drs Petrides, Bates, Lipsitz, Landman, Tanasijevic, and Melanson and Mr Shaykevich). Dr Petrides and Ms Bixho contributed equally.
Context:
- A recent government regulation incentivizes implementation of an electronic health record (EHR) with computerized order entry and structured results display. Many institutions have also chosen to interface their EHR with their laboratory information system (LIS).
Objective:
- To determine the impact of an interfaced EHR-LIS on laboratory processes.
Design:
- We analyzed several different processes before and after implementation of an interfaced EHR-LIS: the turnaround time, the number of stat specimens received, venipunctures per patient per day, preanalytic errors in phlebotomy, the number of add-on tests using a new electronic process, and the number of wrong test codes ordered. Data were gathered through the LIS and/or EHR.
Results:
- The turnaround time for potassium and hematocrit decreased significantly (P = .047 and P = .004, respectively). The number of stat orders also decreased significantly, from 40% to 7% for potassium and hematocrit, respectively (P < .001 for both). Even though the average number of inpatient venipunctures per day increased from 1.38 to 1.62 (P < .001), the average number of preanalytic errors per month decreased from 2.24 to 0.16 per 1000 specimens (P < .001). Overall there was a 16% increase in add-on tests. The number of wrong test codes ordered was high and it was challenging for providers to correctly order some common tests.
Conclusions:
- An interfaced EHR-LIS significantly improved within-laboratory turnaround time and decreased stat requests and preanalytic phlebotomy errors. Despite increasing the number of add-on requests, an electronic add-on process increased efficiency and improved provider satisfaction. Laboratories implementing an interfaced EHR-LIS should be cautious of its effects on test ordering and patient venipunctures per day.
Related Concept Videos
Methods of Documentation VII: EMR
Health Information Technology and Healthcare Information System
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
Integrated Healthcare System
Issues And Trends In Healthcare Delivery System
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Methods of Documentation III: PIE
Purpose of Health Records I
Here's a breakdown of how health records serve these purposes:

