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Cystosarcoma phylloides in the adolescent female.
D L Mollitt1, E S Golladay, E S Gloster
1University of Arkansas for Medical Sciences, Little Rock.
Journal of Pediatric Surgery
|October 1, 1987
Summary
Cystosarcoma phylloides in adolescent females presents as rapidly growing, large breast masses. Surgical excision is effective, with most cases being benign and showing no recurrence after treatment.
Area of Science:
- Oncology
- Surgical Pathology
- Adolescent Medicine
Background:
- Cystosarcoma phylloides is a rare breast tumor.
- Adolescent presentation is uncommon and warrants specific diagnostic considerations.
Purpose of the Study:
- To review clinical characteristics and outcomes of adolescent females with cystosarcoma phylloides.
- To evaluate the efficacy of surgical excision for this rare neoplasm in adolescents.
Main Methods:
- Retrospective case series of five adolescent females treated between 1979 and 1985.
- Surgical excision using circumareolar or inframammary approaches.
- Histopathological analysis to determine tumor type (benign vs. malignant).
Main Results:
- Mean age at presentation was 15 years.
- Common features included rapid growth and large tumor size (mean 7 cm).
- Four benign cases showed no recurrence (mean follow-up 33.8 months); one malignant liposarcoma required mastectomy with no evidence of disease at 35 months.
Conclusions:
- Cystosarcoma phylloides in adolescents often presents as large, rapidly growing masses.
- Surgical excision is a viable treatment option with favorable outcomes for benign lesions.
- Malignant cases require more aggressive surgical management but can have good prognoses with timely intervention.