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Comparing Quality of Life in Smell and Taste Disorders With Other Chronic Conditions-A Narrative Review.

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In Silico Clinical Trials for Cardiovascular Disease
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Cochrane Corner: Extracts from The Cochrane Library.

Richard Orlandi1, Clair Hopkins2, Carl Philpott3

  • 11 University of Utah, Salt Lake City, Utah, USA.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|March 2, 2017
PubMed
Summary

Intranasal steroids offer low- to moderate-evidence benefits for chronic rhinosinusitis symptoms like congestion and runny nose. However, no specific steroid or delivery method is proven superior for treating this condition.

Keywords:
Cochrane Collaborationchronic rhinosinusitisevidence-based medicineintranasal corticosteroidssystematic review

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Area of Science:

  • Otolaryngology-Head and Neck Surgery
  • Evidence-Based Medicine

Background:

  • Chronic rhinosinusitis (CRS) is a common condition affecting the nasal cavity and sinuses.
  • Intranasal steroids are frequently used to manage CRS symptoms.

Purpose of the Study:

  • To summarize findings from Cochrane Reviews on intranasal steroids for CRS.
  • To provide expert commentary to guide clinical decision-making.

Main Methods:

  • Systematic review of Cochrane Reviews.
  • Analysis of evidence for intranasal steroids in CRS.

Main Results:

  • Low- to moderate-quality evidence supports the benefit of intranasal steroids for overall CRS symptoms, nasal congestion, and rhinorrhea.
  • No evidence indicates superiority of specific steroid preparations or delivery systems.

Conclusions:

  • Intranasal steroids demonstrate a beneficial effect in managing chronic rhinosinusitis.
  • Current evidence does not support the preference of one steroid formulation or delivery method over another for CRS treatment.