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Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome
Alessandro Aquino1, Mattia Perini2, Silvia Cosmai2
1Research Department, Istituto Superiore di Osteopatia, 20126 Milan, Italy; Department of Clinical Paediatrics & Obstetrics-Gynaecology, Istituto Superiore di Osteopatia, 20126 Milan, Italy.
Pitt-Hopkins Syndrome (PTHS) is a rare genetic disorder. Osteopathic Manipulative Treatment (OMT) improved bowel function and constipation in a 10-year-old patient with PTHS.
Area of Science:
- Genetics
- Gastroenterology
- Osteopathic Medicine
Background:
- Pitt-Hopkins Syndrome (PTHS) is a rare genetic disorder resulting from TCF4 gene insufficiency.
- Gastrointestinal issues, particularly severe chronic constipation (affecting 75% of patients), are common in children with PTHS.
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