Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

3.0K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
3.0K
Computed Tomography01:10

Computed Tomography

9.2K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
9.2K
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

514
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
514

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oral health skills framework for pregnant women: a professional consensus.

BMC pregnancy and childbirth·2026
Same author

Structural alteration of neurons in schizophrenia and its relation with auditory hallucination.

European psychiatry : the journal of the Association of European Psychiatrists·2026
Same author

Recherche en soins infirmiers·2026
Same author

Autonomous Synthesis and Inverse Design of Electrochromic Polymers with High Efficiency and Accuracy.

Journal of the American Chemical Society·2025
Same author

Pyramidal soma size in the anterior cingulate cortex is small in schizophrenia and correlates with hallucination score.

Psychiatry research·2025
Same author

Use of digital self-care solutions for diabetes long-term management: a scoping review protocol.

BMJ open·2025
Same journal

Correction to: Accuracy of surface strain measurements from transmission electron microscopy images of nanoparticles.

Advanced structural and chemical imaging·2019
Same journal

Optimal principal component analysis of STEM XEDS spectrum images.

Advanced structural and chemical imaging·2019
Same journal

Protein structural biology using cell-free platform from wheat germ.

Advanced structural and chemical imaging·2018
Same journal

Multiscale higher-order TV operators for L1 regularization.

Advanced structural and chemical imaging·2018
Same journal

An open-source software ecosystem for the interactive exploration of ultrafast electron scattering data.

Advanced structural and chemical imaging·2018
Same journal

Sub-Ångstrom electric field measurements on a universal detector in a scanning transmission electron microscope.

Advanced structural and chemical imaging·2018
See all related articles

Related Experiment Video

Updated: Mar 6, 2026

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography
11:33

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography

Published on: January 30, 2016

11.5K

Trace: a high-throughput tomographic reconstruction engine for large-scale datasets.

Tekin Bicer1, Doğa Gürsoy2, Vincent De Andrade2

  • 1Mathematics and Computer Science Division, Argonne National Laboratory, 9700 South Cass Ave., Lemont, IL 60439 USA.

Advanced Structural and Chemical Imaging
|March 7, 2017
PubMed
Summary
This summary is machine-generated.

Trace, a new computing engine, dramatically speeds up computed tomography (CT) data reconstruction. This high-performance engine enables faster scientific discovery by reducing CT data analysis time from hours to minutes.

Keywords:
Big dataHigh-throughputReconstructionTomography

More Related Videos

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT
08:57

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT

Published on: June 21, 2011

19.3K
Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
08:46

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

10.5K

Related Experiment Videos

Last Updated: Mar 6, 2026

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography
11:33

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography

Published on: January 30, 2016

11.5K
High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT
08:57

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT

Published on: June 21, 2011

19.3K
Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
08:46

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

10.5K

Area of Science:

  • Scientific Computing
  • Data Analysis
  • Imaging Science

Background:

  • Modern synchrotron light sources generate massive datasets, necessitating large-scale computation for analysis.
  • Computed tomography (CT) is a key imaging technique producing data at tens of gigabytes per second.
  • Current CT data reconstruction is computationally intensive, often taking days and hindering scientific progress.

Purpose of the Study:

  • To develop a high-performance computing engine for iterative tomographic reconstruction.
  • To enable efficient processing of large-scale CT datasets on parallel computers.
  • To accelerate scientific discovery by reducing data analysis bottlenecks.

Main Methods:

  • Introduced Trace, a data-intensive computing engine for high-performance tomographic reconstruction.
  • Implemented fine-grained shared and distributed memory parallelization.
  • Utilized a novel replicated reconstruction object data structure with specific optimizations.

Main Results:

  • Achieved a 158x speedup using 32 compute nodes (384 cores) compared to a single-core setup.
  • Reduced the reconstruction time for a large sinogram from 12.5 hours to under 5 minutes per iteration.
  • Demonstrated significant performance gains on datasets from the Advanced Photon Source.

Conclusions:

  • The Trace engine efficiently processes large-scale tomographic data.
  • The parallelization and optimization techniques minimize reconstruction times.
  • Accelerated CT data analysis facilitates scientific progress.