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Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
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Bioinspired Helical Microfibers from Microfluidics.

Yunru Yu1, Fanfan Fu1, Luoran Shang1

  • 1State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.

Advanced Materials (Deerfield Beach, Fla.)
|March 8, 2017
PubMed
Summary
This summary is machine-generated.

Researchers developed a microfluidic system to create tunable helical microfibers. These advanced materials offer versatile applications, from microsprings to biological force indicators.

Keywords:
cardiomyocytehelixmagneticmicrofibermicrofluidics

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Area of Science:

  • Materials Science
  • Microfluidics
  • Biotechnology

Background:

  • Helical structures are vital in nature and emerging materials.
  • Unique spiral geometry offers enhanced physical and chemical properties.
  • Fabricating micro/nanoscale helical materials presents significant challenges.

Purpose of the Study:

  • To present a scalable method for generating helical microfibers.
  • To demonstrate precise control over microfiber dimensions and structures.
  • To explore potential applications of these novel helical microfibers.

Main Methods:

  • Utilized a coaxial capillary microfluidic system for spinning and spiraling.
  • Precisely controlled microfiber generation by adjusting flow rates.
  • Varied injection capillary design to achieve diverse helical structures (Janus, triplex, core-shell, double-helix).

Main Results:

  • Achieved scalable generation of helical microfibers with controllable dimensions (length, diameter, pitch).
  • Successfully produced various complex helical microfibers, including novel structures.
  • Demonstrated potential applications in magnetically and thermodynamically triggered microsprings and cardiomyocyte contraction force indication.

Conclusions:

  • The developed microfluidic system enables precise and scalable fabrication of helical microfibers.
  • The versatility of these helical microfibers allows for diverse applications in materials science and biotechnology.
  • This technology opens new avenues for designing functional micro- and nanoscale helical materials.