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Fluorescence-Activated Cell Sorting for the Isolation of Scleractinian Cell Populations
Published on: May 31, 2020
Sesquiterpene constituents from the soft coral Sinularia nanolobata
Ninh Thi Ngoc1,2, Pham Thi Mai Huong1, Nguyen Van Thanh1,2
1a Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST) , Hanoi , Vietnam.
Abstract:
Using various chromatographic separations, four sesquiterpenes (1-4), including two new compounds, nanolobatols A and B (1 and 2), were isolated from the Vietnamese soft coral Sinularia nanolobata. Their structures were determined on the basis of spectroscopic data (1H and 13C NMR, HSQC, HMBC, 1H-1H COSY, NOESY and FT-ICR-MS) and by comparison with the literature values. The cytotoxic activity of isolated compounds against a panel of eight human cancer cell lines was also evaluated.
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