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Updated: Mar 6, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Drug-induced sleep endoscopy: A new gold standard for evaluating OSAS? Part I: Technique
M Blumen1, E Bequignon2, F Chabolle3
1Service ORL, hôpital Foch, 40, rue Worth, 92140 Suresnes, France; Centre médical Veille Sommeil, 59, avenue de Villiers, 75017 Paris, France.
Abstract:
Surgical results in obstructive sleep apnea syndrome (OSAS) vary greatly, whatever the surgical technique or site treated. Most authors agree that rigorous patient selection is logical and mandatory. Drug-induced sleep endoscopy (DISE) was introduced in 1991 and has been rediscovered and used extensively since the 2000s. It mimics sleep in order to observe the upper airway on flexible endoscopy. A review of the DISE literature was performed, and is reported in two parts. The present first part describes the technique: drugs, practical anesthesiologic and ENT modalities, reproducibility, and limitations.
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