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Updated: Mar 6, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
A passage retrieval method based on probabilistic information retrieval model and UMLS concepts in biomedical
Mourad Sarrouti1, Said Ouatik El Alaoui1
1Laboratory of Computer Science and Modeling, FSDM, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
A new method enhances biomedical question answering by improving passage retrieval using UMLS concepts and a probabilistic model. This approach significantly boosts performance in identifying relevant information for biomedical queries.
Area of Science:
- Biomedical Informatics
- Natural Language Processing
- Information Retrieval
Background:
- Passage retrieval is vital for biomedical question answering (QA) systems.
- Open-domain QA faces challenges, particularly in the biomedical field.
- Existing methods require further refinement for effective biomedical QA.
Purpose of the Study:
- To introduce an advanced biomedical passage retrieval method.
- To enhance the accuracy and efficiency of biomedical QA systems.
Main Methods:
- Utilized Stanford CoreNLP for sentence splitting and passage length analysis.
- Employed a probabilistic information retrieval (IR) model (BM25) with stemmed words and Unified Medical Language System (UMLS) concepts.
- Integrated PubMed search and UMLS similarity for initial document retrieval.
Main Results:
- The proposed method demonstrated strong performance on BioASQ datasets.
- Achieved a significant improvement of 6.84% in mean average precision (MAP) over state-of-the-art methods.
- Outperformed existing approaches in identifying relevant passages.
Conclusions:
- Developed an efficient and effective passage retrieval technique for biomedical QA.
- The method offers high mean average precision for retrieving relevant biomedical information.
- This approach contributes to advancing the capabilities of biomedical question answering systems.
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