Related Experiment Video
Updated: Mar 6, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Published on: June 15, 2019
Sepsis Mimicker in an Human Immunodeficiency Virus-Infected Patient
Mackenzie K Morgan1, Joshua D Hartzell1, Jason M Blaylock1
1Department of Infectious Disease, Walter Reed National Military Medical Center, 8960 Brown Drive, Bethesda, MD 20889.
Abstract:
A 22-year-old human immunodeficiency virus-infected male presented with fever, rash, hypotension, and renal insufficiency 18 days following initiation of therapy with an efavirenz-based antiretroviral regimen. Although rash is a common side effect of efavirenz, severe hypersensitivity reactions are rare. Systemic symptoms can include hepatic toxicity and pneumonitis, and in one instance death. Corticosteroids are the mainstay of treatment.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Sexually Transmitted Infections
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

