Microscope-Integrated OCT Feasibility and Utility With the EnFocus System in the DISCOVER Study

Area of Science:

• Ophthalmology
• Medical Imaging
• Surgical Technology

Background:

• Evaluating a novel microscope-integrated intraoperative optical coherence tomography (OCT) system.
• Assessing the feasibility and utility of this technology in ophthalmic surgery.
• Focusing on the EnFocus prototype system within the DISCOVER study.

Purpose of the Study:

• To determine the feasibility and utility of a microscope-integrated intraoperative OCT system.
• To evaluate the impact of intraoperative OCT on surgical decision-making.
• To assess the EnFocus prototype system's performance in ophthalmic procedures.

Main Methods:

• The DISCOVER study involved imaging 50 eyes with the EnFocus intraoperative OCT system.
• OCT imaging was performed at surgeon-determined points during ophthalmic surgery.
• Surgeons completed post-operative questionnaires to report OCT's influence on management.

Main Results:

• Successful imaging was achieved in 92% of cases (46 out of 50 eyes).
• Intraoperative OCT findings led to changes in surgical management in 16% of cases (8 out of 50).
• In membrane peeling, OCT findings differed from initial surgical impressions in 35% of cases (7 out of 20).

Conclusions:

• The study confirms the feasibility of microscope-integrated intraoperative OCT with the Bioptigen EnFocus system.
• Intraoperative OCT can offer surgeons supplementary information, potentially altering surgical decisions.
• This technology holds promise for enhancing ophthalmic surgical procedures.