Related Experiment Video
Updated: Mar 6, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
Published on: July 29, 2013
Quantitation of clinical feedback on image quality differences between two CT scanner models.
Steven T Bache1, Paul J Stauduhar1, Xinming Liu1
1Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030-3722, United States.
GE CT scanner models showed differences in image quality. The Discovery HD750 (HD) had higher noise, while the LightSpeed VCT (VCT) demonstrated superior low contrast detectability (LCD), aligning with radiologist feedback.
Area of Science:
- Medical Imaging
- Radiology
- CT Technology
Background:
- Radiologist feedback indicated perceived differences in image quality between GE LightSpeed VCT (VCT) and Discovery HD750 (HD) CT scanner models.
- Quantitative assessment of image quality parameters is crucial for optimizing diagnostic performance.
Purpose of the Study:
- To quantitatively compare image quality metrics, specifically noise and low contrast detectability (LCD), between GE VCT and HD CT scanner models.
- To validate radiologist observations regarding scanner performance differences.
Main Methods:
- Analysis of 3 years of Quality Control (QC) phantom images from five VCT and five HD scanners to measure noise magnitude (CT-number standard deviation) and noise power spectrum (NPS).
- Low contrast detectability (LCD) assessment using a phantom scanned on four VCT and four HD scanners.
- Image quality evaluation on an anthropomorphic phantom using eight scanners, with regions of interest in the abdomen (liver, stomach, spleen).
Main Results:
- GE HD scanners exhibited an 8.5% higher noise magnitude compared to VCT scanners.
- Noise power spectra magnitude increased with noise, but peak and mean NPS frequencies were similar between models.
- VCT scanners achieved an average of 13.1% better LCD performance than HD scanners across all phantoms and scanners.
Conclusions:
- GE VCT scanners demonstrate superior low contrast detectability compared to HD scanners.
- Higher noise levels in HD scanners correlate with observed image quality differences.
- Findings support radiologist feedback and highlight the need to review and optimize body CT protocols across different scanner models.
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

