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Porokeratosis simulating Bowen's disease on dermoscopy.

Alzinira Sousa Herênio1, Silvana Maria de Morais Cavalcanti2, Emmanuel Rodrigues de França2

  • 1Universidade de São Paulo (USP) - São Paulo (SP), Brazil.

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Summary

Porokeratosis, a keratinization disorder, presents as annular plaques. This case highlights its association with chronic lymphedema and mimics Bowen's disease on dermoscopy.

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Porokeratosis is a rare disorder of epidermal keratinization.
  • Its exact cause is unknown, but it may be linked to weakened immune systems.

Observation:

  • A patient with chronic lymphedema presented with porokeratosis.
  • Clinical and dermoscopic examinations showed annular hyperkeratotic plaques resembling a "volcanic crater contour" (cornoid lamella).
  • The lesions shared features with Bowen's disease, including numerous glomerular vessels.

Findings:

  • Dermoscopy is crucial for identifying the characteristic cornoid lamella in porokeratosis.
  • The case demonstrates a potential association between porokeratosis and chronic lymphedema.
  • Porokeratosis can clinically and dermoscopically resemble other skin conditions like Bowen's disease.

Implications:

  • This case expands the understanding of porokeratosis presentation and potential associations.
  • Dermoscopy aids in differentiating porokeratosis from other annular skin lesions.
  • Further research may clarify the link between lymphedema and porokeratosis development.