Porokeratosis simulating Bowen's disease on dermoscopy

Area of Science:

• Dermatology
• Pathology

Background:

• Porokeratosis is a rare disorder of epidermal keratinization.
• Its exact cause is unknown, but it may be linked to weakened immune systems.

Observation:

• A patient with chronic lymphedema presented with porokeratosis.
• Clinical and dermoscopic examinations showed annular hyperkeratotic plaques resembling a "volcanic crater contour" (cornoid lamella).
• The lesions shared features with Bowen's disease, including numerous glomerular vessels.

Findings:

• Dermoscopy is crucial for identifying the characteristic cornoid lamella in porokeratosis.
• The case demonstrates a potential association between porokeratosis and chronic lymphedema.
• Porokeratosis can clinically and dermoscopically resemble other skin conditions like Bowen's disease.

Implications:

• This case expands the understanding of porokeratosis presentation and potential associations.
• Dermoscopy aids in differentiating porokeratosis from other annular skin lesions.
• Further research may clarify the link between lymphedema and porokeratosis development.