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Hepatocellular carcinoma: molecular biology, etiology and animal models
1Liver Unit, University of the Witwatersrand Medical School, Johannesburg, South Africa.
Gastroenterology Clinics of North America
|December 1, 1987
Abstract:
Hepatocellular carcinoma (HCC) occurs uncommonly in the United States and Western Europe, but is a relatively frequent neoplasm in sub-Saharan Africa, China, and the Far East. Environmental factors appear to determine the geographic clustering of the disease and to cause different spectrums of the disease in the high-incidence and low-incidence areas of the world.