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Pulmonary Tuberculosis IV

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

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Updated: Mar 6, 2026

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection

Published on: February 16, 2020

Nanodiagnostics for tuberculosis detection.

Hesham El-Samadony¹, Asma Althani², Mohamed Awad Tageldin³

¹a Ministry of Health , Abbassia Chest Hospital , Cairo , Egypt.

Expert Review of Molecular Diagnostics

|March 21, 2017

Summary

This summary is machine-generated.

Nanoparticle-based diagnostics offer a promising approach for early, accurate, and affordable detection of tuberculosis (TB). These novel TB nanodiagnostics cover various forms of the disease, aiding the global End TB strategy.

Keywords:

Tuberculosis VOCs gold nanoparticles immunodiagnostics isoniazid nanoassays nanodiagnostics nucleic acid markers protein markers rifampicin volatile compounds. MDRTB

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Last Updated: Mar 6, 2026

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection

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Area of Science:

Nanotechnology in infectious disease diagnostics
Biomarker detection for Mycobacterium tuberculosis

Background:

Tuberculosis (TB) remains a major global health threat, necessitating improved diagnostic tools.
Current diagnostic methods for TB are often insufficient in terms of speed, cost, or accuracy.
The End TB strategy targets epidemic elimination by 2030, highlighting the need for advanced diagnostics.

Purpose of the Study:

To review the state-of-the-art in TB nanodiagnostics over the past decade.
To assess the fabrication, detection strategies, and clinical performance of nanoparticle-based TB assays.
To evaluate the potential of nanodiagnostics to meet the demands for ideal Mycobacterium tuberculosis (MTB) testing.

Main Methods:

Comprehensive literature review of TB nanodiagnostics characterized in the last 10 years.
Analysis of approximately thirty-five TB NP-based assays.
Focus on fabrication concepts, detection strategies, and clinical performance across diverse specimens.

Main Results:

Numerous TB nanodiagnostics exhibit accuracy, low cost, and rapid results.
These nanodiagnostics address various TB manifestations, including active, latent, drug-resistant, and co-infections.
The reviewed platforms demonstrate significant advancements in TB detection capabilities.

Conclusions:

TB nanodiagnostics show considerable promise as ideal tools for TB detection.
These technologies have the potential to significantly contribute to achieving the End TB epidemic goals by 2030.
Further development and clinical validation are crucial for widespread implementation.