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Autogenic Drainage in Children With Cystic Fibrosis

Lieselotte Corten1, Brenda M Morrow

  • 1Department of Health and Rehabilitation Sciences, Physiotherapy (Ms Corten), University of Cape Town, Observatory, South Africa; and School of Child and Adolescent Health, Paediatric Critical Care and Children's Heart Disease (Dr Morrow), University of Cape Town, Red Cross War Memorial Children's Hospital, Rondebosch, South Africa.

Pediatric Physical Therapy : the Official Publication of the Section on Pediatrics of the American Physical Therapy Association
|March 21, 2017
PubMed

Insights

Autogenic drainage (AD) may improve airway clearance in cystic fibrosis (CF) children, but more research is needed. Current evidence for AD and assisted autogenic drainage (AAD) in pediatric CF patients is insufficient.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Cystic Fibrosis Management

Background:

  • Airway clearance is crucial for managing cystic fibrosis (CF).
  • Viscous pulmonary secretions in CF necessitate effective clearance techniques.
  • Autogenic drainage (AD) and assisted autogenic drainage (AAD) are airway clearance methods.

Purpose of the Study:

  • To evaluate the efficacy of autogenic drainage (AD) and assisted autogenic drainage (AAD) in children with CF.
  • To compare AD and AAD against no, sham, or other airway clearance methods.
  • To synthesize current evidence on AD and AAD for pediatric CF airway clearance.

Main Methods:

  • Systematic review of pediatric randomized cross-over trials.
  • Inclusion of studies comparing AD and AAD with control groups (no, sham, or other techniques).
  • Analysis of available data on AD and AAD in children with CF.

Main Results:

  • Two pediatric randomized cross-over trials on AD were identified; no studies on AAD were found.
  • One study indicated AD positively influenced the Huang score, favoring it over postural drainage.
  • Insufficient data exists to definitively determine the efficacy of AD and AAD in pediatric CF.

Conclusions:

  • The efficacy of autogenic drainage (AD) and assisted autogenic drainage (AAD) in children with cystic fibrosis (CF) cannot be determined from current research.
  • Further pediatric-specific randomized controlled trials with robust methodologies are recommended.
  • Future studies should focus on adequate sample sizes, appropriate clinical outcomes, and adverse effect analysis.
Abstract

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