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Reduced field of view single-shot spiral perfusion imaging
Yang Yang1, Li Zhao2, Xiao Chen3
1Departments of Medicine, Cardiovascular Division, University of Virginia Health System, Charlottesville, Virginia, USA.
Magnetic Resonance in Medicine
|March 22, 2017
Summary
A new single-shot spiral perfusion MRI technique uses outer-volume suppression (OVS) to improve whole-heart coverage. This method achieves high-quality perfusion imaging with a significantly reduced temporal footprint, enhancing diagnostic accuracy.
Area of Science:
- Cardiovascular Imaging
- Magnetic Resonance Imaging (MRI)
Background:
- Perfusion imaging is crucial for diagnosing cardiovascular diseases.
- Current MRI techniques face challenges in achieving whole-heart coverage with adequate temporal resolution.
Purpose of the Study:
- To develop and validate a novel single-shot spiral perfusion pulse sequence incorporating outer-volume suppression (OVS).
- To achieve whole-heart coverage with a minimal temporal footprint (10 ms per slice).
Main Methods:
- A highly accelerated single-shot variable density spiral pulse sequence with an integrated OVS module was developed.
- The sequence was evaluated using simulations, phantom experiments, and clinical studies (n=16).
- Images were reconstructed using block low-rank sparsity with motion guidance (BLOSM) and assessed by cardiologists.
Main Results:
- Outer-volume suppression (OVS) effectively minimized signal outside the desired field of view (FOV).
- Clinical data demonstrated high-quality perfusion images with reduced FOV (rFOV).
- Cardiologist assessments showed significantly superior image quality for rFOV images compared to full FOV images (P < 0.05).
Conclusions:
- The developed single-shot spiral perfusion sequence with OVS and BLOSM enables high-quality perfusion imaging.
- The technique supports whole-heart coverage with a very short temporal footprint per image.
- This advancement offers improved diagnostic capabilities in cardiovascular MRI.
