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Published on: May 22, 2020
Multifunctional Inorganic Nanoparticles: Recent Progress in Thermal Therapy and Imaging
Kondareddy Cherukula1, Kamali Manickavasagam Lekshmi2, Saji Uthaman3
1Department of Biomedical Science and BK21 PLUS Centre for Creative Biomedical Scientists, Chonnam National University Medical School, Gwangju 501-746, Korea. cherrikonda@gmail.com.
Multifunctional inorganic nanoparticles offer advanced image-guided cancer thermal therapies. These nanoparticles integrate imaging and treatment, minimizing side effects and improving disease identification for better patient outcomes.
Area of Science:
- Nanomedicine
- Biotechnology
- Materials Science
Background:
- Cancer treatment faces challenges in precise disease identification and targeted therapy delivery.
- Minimally invasive thermal therapies offer an alternative to traditional treatments, reducing damage to healthy tissues.
- Image-guided therapies enhance diagnostic accuracy and treatment efficacy by combining imaging and therapeutic functions.
Purpose of the Study:
- To review recent advancements in thermal therapy and imaging integrated with multifunctional inorganic nanoparticles.
- To explore inorganic nanoparticles for image-guided cancer treatment.
- To discuss the clinical perspectives and future scope of these nanomaterials.
Main Methods:
- Focus on inorganic nanoparticles for surface plasmon resonance (SPR) and alternating magnetic field (AMF) based thermal therapies.
- Description of nanoparticle families used for SPR- and AMF-based therapies and imaging.
- Presentation of nanomaterials for multimodal therapies and multi-imaging modalities.
Main Results:
- Inorganic nanoparticles enable integrated thermal therapy and imaging for cancer treatment.
- SPR and AMF are key heating sources for heat-induced therapies.
- Multifunctional nanomaterials support diverse therapeutic approaches and imaging techniques.
Conclusions:
- Inorganic nanoparticles are promising for image-guided cancer therapies.
- Integration of imaging and thermal therapy offers improved treatment precision and reduced side effects.
- Further clinical research is needed to realize the full potential of these nanotechnologies in oncology.

