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Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution
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Mimicking pH-Gated Ionic Channels by Polyelectrolyte Complex Confinement Inside a Single Nanopore.

Yixuan Zhao1, Jean-Marc Janot1, Emmanuel Balanzat2

  • 1Institut Européen des Membranes, UMR5635 UM ENSM CNRS, Place Eugène Bataillon, 34095 Montpellier cedex 5, France.

Langmuir : the ACS Journal of Surfaces and Colloids
|March 28, 2017
PubMed
Summary

Researchers developed a novel pH-gated nanopore using layer-by-layer assembly of polyethylenimine and chondroitin-4-sulfate (ChS). This artificial channel exhibits anion selectivity and pH-dependent gating, opening below pH 4-5.

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