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RF slice profile effects in magnetic resonance fingerprinting
Taehwa Hong1, Dongyeob Han1, Min-Oh Kim1
1Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Republic of Korea.
Magnetic Resonance Imaging
|April 10, 2017
Summary
Radio frequency slice profiles impact magnetic resonance fingerprinting (MRF) T1 and T2 estimations. Compensating for these non-ideal effects is crucial for accurate MR parameter determination.
Area of Science:
- Medical Imaging
- Physics
Background:
- Magnetic Resonance Fingerprinting (MRF) enables rapid quantitative MRI.
- Accurate T1 and T2 mapping is essential for various clinical applications.
- Non-ideal radio frequency (RF) slice profiles can introduce artifacts in MR imaging.
Purpose of the Study:
- To investigate the impact of RF slice profile imperfections on T1 and T2 estimation in MRF.
- To evaluate how factors like time-bandwidth product (TBW), flip angle (FA), and field inhomogeneities influence these errors.
- To determine the necessity of correcting for RF slice profile effects in MRF.
Main Methods:
- Bloch simulations were used to generate signal evolutions considering non-ideal RF slice excitation.
- MRF dictionaries were created with and without accounting for slice profile effects.
- Phantom and in vivo experiments were conducted at 3 Tesla for validation.
Main Results:
- Simulations and experiments demonstrated that T1 and T2 estimation errors increase with higher FA levels.
- Errors were also found to increase with greater off-resonance and lower TBW values.
- The deviation from ideal slice profiles directly correlates with parameter estimation inaccuracies.
Conclusions:
- RF slice profile effects significantly influence T1 and T2 accuracy in MRF.
- These effects are exacerbated by high flip angles, field inhomogeneities, and low TBW.
- Compensation for RF slice profile imperfections is necessary for precise MR parameter quantification.