Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ultra-High Spatial Resolution, Multi-Energy CT using Photon Counting Detector Technology.

S Leng1, R Gutjahr2, A Ferrero1

  • 1Department of Radiology, Mayo Clinic, Rochester, MN.

Proceedings of Spie--The International Society for Optical Engineering
|April 11, 2017
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adoption of electronic patient-reported outcomes in cancer clinical practice: the point of view of Italian patients.

ESMO real world data and digital oncology·2026
Same author

Long-Range Transverse-Momentum Correlations and Radial Flow in Pb-Pb Collisions at the LHC.

Physical review letters·2026
Same author

PARPi and myeloid neoplasms; the Italian MITO-MaNGO experience based on a multicentric survey.

ESMO open·2025
Same author

Search for Quasiparticle Scattering in the Quark-Gluon Plasma with Jet Splittings in pp and Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

Physical review letters·2025
Same author

Adaptive-driven CT simulation-free multi-fraction SBRT radiotherapy: Initial clinical experience.

Journal of applied clinical medical physics·2025
Same author

Intra- and peri-meniscal polynucleotide injections for the treatment of symptomatic degenerative meniscus of the knee: 1-year findings from a prospective clinical trial.

European review for medical and pharmacological sciences·2025
Same journal

From Geometry to Intensity: A Coarse-to-Fine Pipeline for Unsupervised 3D Ultrasound Stitching.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same journal

AVA: Automated Viewability Analysis for Ureteroscopic Intrarenal Surgery.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same journal

Kidney Endoscopy Video to Preoperative CT Alignment for Depth Estimation.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same journal

Deep learning‑based cell type prediction in lung tissue from brightfield histology using CODEX-derived labels.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same journal

Reconstructing physiological signals from fMRI across the adult lifespan.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same journal

Axially Swept Light-Sheet Microscopy using scattering and fluorescence contrast mechanisms.

Proceedings of SPIE--the International Society for Optical Engineering·2026
See all related articles
This summary is machine-generated.

Ultra-high-resolution (UHR) CT imaging improves anatomical detail for kidney stones and lung nodules. However, higher radiation doses or noise reduction are needed for accurate multi-energy analysis with UHR photon-counting-detector CT.

Area of Science:

  • Medical Imaging
  • Radiology
  • Photon-Counting Detector CT

Background:

  • Photon-counting detector (PCD) CT scanners offer advanced imaging capabilities.
  • Ultra-high-resolution (UHR) and sharp imaging modes were developed for PCD CT.
  • Standard (macro) mode provides a baseline for comparison.

Purpose of the Study:

  • To evaluate and compare UHR and sharp imaging modes against standard macro mode on a whole-body PCD CT scanner.
  • To assess the impact of higher spatial resolution on anatomical delineation and multi-energy analysis.
  • To determine the optimal conditions for utilizing UHR imaging capabilities.

Main Methods:

  • Implementation of two UHR imaging modes (UHR and sharp) with dual energy thresholds on a research PCD CT scanner.
Keywords:
Computed tomography (CT)dual energyhigh resolutionphoton counting detector (PCD)

Related Experiment Videos

  • Scanning of kidney stones and lung nodules using UHR, sharp, and standard macro modes.
  • Comparative analysis focused on spatial resolution for anatomical structures and multi-energy quantification of stone composition.

    • Main Results:

    • UHR and sharp modes provided enhanced shape and texture information for anatomical structures due to higher spatial resolution, albeit with increased noise.
    • No significant benefit in multi-energy analysis was observed with UHR compared to macro mode at standard radiation doses, attributed to noise.
    • UHR scans at higher doses demonstrated improved multi-energy analysis compared to macro mode at regular doses.

    Conclusions:

    • Higher spatial resolution in UHR CT enhances anatomical detail but requires careful consideration of noise levels.
    • Achieving the full potential of UHR imaging for multi-energy analysis necessitates either increased radiation dose or advanced noise reduction techniques.
    • Future applications of UHR PCD CT for quantitative analysis may benefit from optimized dose protocols or denoising algorithms.